Ethnicity denotes the synthesis of biological and Active ancestry and cultural elements. Ethnicity is a critical attribute of race in that it is a basis of diversity within and between racial categories. Race and tribe are special forms of social organization and stratification associated with certain historical and political economic conditions; ethnicity is a more universal human attribute. This chapter presents suggestions as to how we can best create qualitative research methods indigenous to the experiences of Afro-Americans and other people of color in the United States. Conventional concerns about data interpretation and knowledge dissemination have focused on the ethnocentrism tradition that drives so much American and other Western social research on people of color, including those perspectives that claim to be radical and liberating. The racialized ethnic differences between white women and women of color in multiracial nation-states must be taken into consideration if one is to understand the erroneous ways in which concepts drawn from the experiences.