ABSTRACT
Studies in healthy adults have shown that intranasal oxytocin increases trust. Does oxytocin have the same effect on individuals with borderline personality disorder (BPD) as it does on healthy individuals? At first glance, it would seem possible to answer this question by designing a study restricted to individuals with BPD. This chapter makes us to learn about various types of effects that can be tested in a factorial design. It shows that the biofeedback main-effect contrast was orthogonal to the drug therapy main-effect. The chapter considers designs where the groups are defined by two or more factors. Measures of effect are just as relevant in factorial designs as in single-factor designs. The only real difference is that the presence of multiple factors leads to yet additional ways of conceptualizing measures of effect.
