Pharmacokinetic Factors that Modify Drug Action

After completing this chapter, the reader should be able to:

describe the ways in which drug absorption is altered by disease, diet, exercise and pregnancy, and the consequent effects on drug action;

name the ways in which drug distribution is altered by disease and pregnancy, and the consequent effects on drug action;

list the ways in which drug metabolism is altered by disease, occupation and diet, and the consequent effects on drug action;

describe the ways in which drug excretion is altered by disease, and the consequent effects on drug action.