This chapter considers some of the needs, challenges, and interventions for working therapeutically within children’s residential homes, occupied by Looked after Children (LAC). Residential homes should be an important focus under the relational and developmental trauma umbrella, as although they tend to represent only a small proportion of the UK’s LAC population, they often care for the most vulnerable, complex, risky, and marginalised children. The term residential children’s home is broad and encompasses many different types of homes, and multiple variations within them. Furthermore, residential care serves different functions depending on the local borough and service needs. Adding to this complexity are the unique subcultures and group climates which are found within each home. Table 11.1 illustrates some of the varying residential home categories.