ABSTRACT

Dementia means loss of mind' and is one of two mind-destroying disorders, the other being schizophrenia. Dementia with cortical Lewy bodies (DCLB) accounts for about 10" of all dementias, but about 20" of AD patients also have cortical Lewy bodies. The hippocampus is situated within the hippocampal fissure, close to the parahippocampal gyrus, part of the temporal lobes on both sides. This area is sometimes called the hippocampal complex or hippocampal formation, because several structures occur close together and have many interconnections with each other. The hippocampus has several important roles. These include the conversion of short-term memory to long-term memory and influencing thinking through connections with the frontal cortex. Pick's disease, also called frontotemporal dementia (FTD) or frontotemporal lobar degeneration (FTLD) was described in 1892 by Arnold Pick, earlier than the description of Alzheimer's disease.