The primal epistemology of the Islamic worldview is premised on Divine Unity, referred to in the Qur’an as Tawhid. The essential precept of Tawhid is the Unity of Complete and Perfect Stock of Knowledge that governs and guides supremely over creation from its beginning to end. This chapter explains the interactive, integrative and evolutionary process oriented Qur’anic worldview as a mathematical system. Through it the epistemology of Divine Unity can be shown to be mobilized through unification of knowledge into factual problems of experience. The use of inverse mappings and multiple extensions of branches of the tree model emanating from Tawhidi epistemology; will be extended to establish the principle of universal complementarity. This principle is a natural corollary to the globally interactive, integrative and evolutionary worldview that is established by the unification of knowledge as derived from the precept of Divine Unity.