The German government paid close attention to output leading to a seminal report from the World Economic Forum’s Global Agenda Council on Water Security which identified the Nexus as a – perhaps the – defining sustainability challenge for the planet. Changes to achieve growth or security in one category can exacerbate or even create problems where none existed in one or both of the other components of the Nexus. It was fitting to host the Bonn Nexus conference in the former government complex, as both the meeting complex and the topic were powerful symbols of dramatic change. The moral and ethical perspective certainly supports well-being: growth must include equity in access to resources, the “democratization” of access to energy–water–food. Growth cannot be infinite yet growth is needed, to restore unhealthy ecosystems, eradicate poverty and gross income inequality, end hunger and malnourishment, and so much more. The chapter also presents an overview of key concepts discussed in this book.