Tough decisions most often involve a tradeoff with one entity not getting what they seek or being forced to accept only some portion of their objective. The person in a position of authority making that decision will face consequences. As many of the changes from tough decisions that need to be made will induce stress among the many, policymakers and decision-makers would be wise to understand and accept these responses and allow for time for more people to reach understanding and be open to debate. At a minimum, action needs to progress through difficult decision-making while advancing knowledge gaps. In doing so, it is important to leave room for adjustment in policy, treaties, and other decisions, to allow for flexibility as more becomes known. Before facing tough decisions, it is important, in the context of the challenges, to accept that the choices must be made.