This chapter begins with a genealogical exploration and operationalization of the Western ‘subject’ and major modern and postmodern notions of Western subjectivity. The reconceptualization of the subject with its nascence in the node of Friedrich Nietzsche has rhizomatically proliferated into what Mansfield terms the “Anti-Subjectives” or the theoretical school of thought that holds the idea of the subject and thus the notion of subjectivity is a mere illusory invention of language. In a poststructuralist read of Nietzsche and indeed the knot of agreement binding the Anti-Subjectivists is the complicity and the imprisonment of language in the construction of the illusion of moral categories and responsibility. Buddhism and other indigenous onto-epistemologies, knowingly or unknowingly, has released all things from the shackles of universal truth and chains of knowledge exposing the “fertile ground of pure creativity and freedom”.