Hospital-acquired infections (HAIs) are health incidents inflicted by the hospital itself. There are three health incidents that can be inflicted during someone's stay in the hospital: medical error, nosocomial, and hospitalization. HAIs as a result of caring complexity also increase caring complexity, creating a cycle that is potentially continuous and fatal. For hospitals, there is a dilemma. HAI individually may increase the diagnosis-related group index and thus increase the hospital's profit from medical treatment. Costs spent by the hospital include: Direct cost and indirect costs. Hospitals are the most likely location for the occurrence of disease spread. Many patients with various conditions, especially infectious diseases, gather in a hospital. Evolution causes bacteria in hospitals to become resistant to antibiotics. The price of medicine is only one part of its economical aspects. To measure more comprehensively, the incremental cost-effectiveness ratio can be used.