ABSTRACT

The chronic gastric achylia that occurs in hamadryas baboons subjected to immobilization neurosis generally develops as a functional disease. At some stage of this neurogenic disorder, however, dystrophic changes have invariably appeared in the mucosa, usually as adenomatous foci and sometimes as multiple polyps and ulcers; anacidosis has been a constant finding. Einhorn, in 1892, introduced the term "achylia gastrica" for those conditions in which there is no indication that the stomach is producing gastric juice. The case histories he described were similar clinically to syndromes involving atrophy of the gastric mucous membrane but they did not represent serious, incurable disease. The detection of spontaneous gastric achylia in monkeys is of special interest, because the investigation of such cases can throw light on a number of the questions regarding etiology and treatment that have arisen from clinical studies of the disease in man.