ABSTRACT
One of the most clearcut and constant findings in the chronic neurogenic gastric achylia of hamadryas baboons is the formation of adenomatous polyps, principally in the pyloric antral area and along the transition zone to the body of the stomach. In the opinion of many clinicians, achylia of many years duration is a relatively high-risk indicator for precancerous lesions of the stomach. Experiments in which neoplastic processes are induced or potentiated by the chronic application of various agents and other experimental conditions have special relevance for the problem of the pathogenesis of precancerous lesions. The appearance of adenomatous polyps or of chronic ulcers in combination with adenomata becomes direct evidence for the development of precancerous lesions of the stomach. The first signs of hyperplasia of the gastric glandular epithelium in hamadryas baboons with neurogenic gastric achylia were seen in the area of the gastric fistula.
