ABSTRACT
In medicine as well as in drug addiction, other routes of entry include injection either subcutaneously, intramuscularly, or intravenously. Intraperitoneal administration, meaning injecting the drug or neurotoxic agent directly into the outer limits of the abdominal cavity, is often used in laboratory animals. Neurotoxic agents and drugs have a differential effect on children, adults, and the elderly. This is primarily because of differences in the rate of absorption in the gastrointestinal tract and the liver’s capacity to metabolize chemical substances. In epidemiological studies of neurotoxic illness, biological factors associated with ingestion, distribution, and metabolism and psychological and cultural factors such as eating habits are sometimes difficult to disentangle. The physiological activity of an individual at the moment of examination is important in the estimation of the pharmacological properties of neurotoxic agents. Feeding, physical exercise, and emotional state are examples of physiological conditions that have been extensively investigated.
