ABSTRACT

Mucoadhesive dosage forms can provide a localized delivery of medicinal agents to a specific site in the body. The ability of mucoadhesive dosage forms to provide an intimate contact of the delivery system with the absorbing corneal layer would undoubtedly improve ocular bioavailability. The intimate contact may result in high drug concentration in the local area and hence high drug flux through the absorbing tissue. The intimate contact may also increase the local permeability of high molecular weight drugs such as peptides and proteins (1).