ABSTRACT

This decreases the probability of an action potential being generated.

16.1.1.4 Action Potential Details of the AP are shown in Figure 16.1.

Neuronal stimulation leads to local depolarization. If (degree of depolarization) > (a critical threshold) →

nerve impulse or AP During an AP, the membrane potential rapidly

becomes positive, before returning to become negative. This is caused by an increase rst in Na+ permeability, allowing the inow of Na+, and then in K+ permeability (with a rapid reduction in Na+ permeability at the same time), causing an outow of K+ and thereby restoring the

negative membrane potential. The sodium pump then restores the original ionic concentrations.