ABSTRACT
Many polyphenols plays a pivotal role in the treatment of many diseases, including neurodegenerative disorders (NDs). Resveratrol has long been used in the treatment of NDs. It exerts its protective effect via multiple pathways, such as antioxidant, anti-inflammatory, and antiamyloidogenic cleavage. However, resveratrol also exhibits several disadvantages, such as low solubility and low bioavailability. To overcome these challenges associated with resveratrol, several drug delivery systems were evaluated, a few of which resulted in profound improvements in the therapeutic efficacy of resveratrol. This chapter throws light on some of the pathways by which resveratrol achieves neuroprotection, and the drug delivery systems used to overcome innate challenges, such as low bioavailability.
