ABSTRACT
The main symptom of ovarian hyperstimulation syndrome (OHSS) is third-space fluid sequestra tion due to generalized capillary leakage1. The loss of serum causes hemoconcentration and kidney failure from hypovolemic shock2. Symp toms of OHSS are aggravated by an increase in von Willebrand factor, resulting in thrombosis in atypical parts of the body or in embolism of the lung or brain3’4. Human chorionic gonadotropin (hCG) exacerbates all symptoms5. This severe condition after controlled ovarian stimulation (COS) results from substances which are obviously produced by the ovaries6. Bilateral ovariectomy will immediately resolve this critical situation7.
