ABSTRACT

This study was conducted in vitro with the aim to determine the antibacterial inhibition activity of encapsulated temulawak (Curcuma Xanthorrhiza Roxb) against lactic acid bacteria, Salmonella and Escherichia coli have 6 different treatments to be observed, namely; (T0) negative control (distilled water), (T1) positive control (tetracycline + distilled water), (T2) temulawak encapsulation 25% + distilled water, (T3) temulawak encapsulation 50% + distilled water, (T4) temulawak encapsulation 75% + distilled water, and (T5) temulawak encapsulation 100% + distilled water. The results of the research on the inhibitory power of temulawak encapsulation in the T5 treatment with a concentration of 100% had a diameter of the inhibition zone against E. coli bacterial activity. where there was a very significant difference (P<0.01). This indicates that temulawak encapsulation is effective in inhibiting E. coli bacteria. In contrast, the antibacterial activity of temulawak encapsulation against LAB bacteria and Salmonella has not shown effective results because the highest value is found in the T1 treatment (0.1% antibiotic); for other treatments (T0, T2, T3, T4, and T5), it has a value of 0.0 mm, and there is no significant effect (P<0.05). Therefore, the use of temulawak encapsulation has not given positive results in inhibiting the growth of lactic acid bacteria and Salmonella.