ABSTRACT
Electrohydrodynamic (EHD) processes, involving techniques such as electrospraying (ESR) and electrospinning (ESI), have emerged as powerful tools in fluid dynamics under the influence of electric fields. These methods play a crucial role in the advancement of microencapsulation and biotissue engineering, enabling the production of micro/nanoparticles and fibers that are essential for applications such as targeted drug delivery, wound healing, and controlled release systems. This chapter explores the key factors influencing the EHD process, including the impact of high voltage (HV), flow rate, working distance, and needle size, along with the role of natural and synthetic polymers in achieving desired dosage forms that are biodegradable, stable, and enhance bioavailability. Additionally, the chapter highlights the potential of EHD-fabricated drug delivery systems, their routes of administration, and the challenges of manufacturing scale-up that help in transitioning from laboratory-scale production to commercial manufacturing. EHD techniques are expected to play an increasingly important role in developing innovative therapeutic solutions, and their adaptability makes them a promising platform for future-generation drug delivery systems.
