ABSTRACT
Objective: Analysis of combined cube scaffold hydroxyapatite with amniotic membrane to compressive strength and swelling ability. Method: Cubes of hydroxyapatite were prepared and immersed in fresh amnion membrane slurry for 5 minutes. After the amnion membrane slurry was fully absorbed by hydroxyapatite, frozen for 24 hours at -80°C and dried-frozen for 24 hours at -100°C. After the cube was fabricated, compressive strength and swelling ability were tested in 10 samples each. The swelling test was carried out at 1, 7, 14, 21, and 28 days. Results: The mean value of compressive strength (2.72±0.64) MPa. The swelling ability percentage on days 1, 7, 21, and 28 in consecutive (78.75±18.65), (86.40±18.65), (89.99±18.65), (94.83±18.65), (100.00±18.65) showed increased and statistical analysis with repeated ANOVA post hoc Bonferroni showed significantly different (p<0.05). Conclusion: The compressive strength and swelling ability of cube hydroxyapatite with amnion membrane shows potential as a scaffold for a bone defect.
