ABSTRACT

Objective: The Study aims to ascertain the effects of administering 0.8% HA gel on bone regeneration following alveolar bone damage. Methods: Samples were divided into two groups: P1 (control) and P2 (treatment). In P1, only alveolar bone damage was induced, while in P2, HA was applied to the damaged alveolar bone. On the 7th day, the rats were euthanized, and their mandibles were collected for histological preparation and data analysis. Result: The mean value of osteoblasts showed a higher value in the P2 group than the P1 group, that is 23.44±8.61 (P2) and 38.18±9.99 (P1). In contrast, the mean value of osteoclast showed a lower value in P2 than the P1 group, that is, 1.27±0.57 (P2) and 4.05±1.25 (P1). Conclusion: These results indicate a significant improvement in bone regeneration in the P2 group, demonstrating the positive effect of 0.8% HA gel on alveolar bone healing.