ABSTRACT
Objectives: to identify which antihypertensive drugs cause the highest rate of dry mouth. Methods: The research was conducted using the PRISMA guidelines. The data collection of the articles used was generated from Google Scholar, PubMed, Semantic, and CrossRef from 2019-2024 on topics related to xerostomia and antihypertensive drugs in the elderly, given the physiological and pharmacological complexity of this age group. Despite only receiving results from 4 reviewed articles were performed to find potential eligible studies, the small number of databases did not significantly affect the study result. Results: The frequency of dry mouth significantly differed among the antihypertensive medication groups (p = 0.008). Calcium channel blockers exhibited the highest rate of dry mouth (31.1%), followed by diuretics (26.8%). Conclusion: The review of articles in this study found antihypertensive medications, calcium channel blockers, which include amlodipine, and diuretics were associated with the highest rates of dry mouth.
