ABSTRACT

Parkinson's disease is the second most common neurodegenerative disorder after Alzheimer's disease. It is a progressive and disabling disease with significative impact on quality of life. Since it has no cure, available treatment is targeted to improve the symptoms due to a lack of dopamine in the central nervous system.

In this chapter, we summarized the currently available therapeutic strategies to manage the early and advanced stages of the disease.

As the disease progresses, treatment becomes more complex and it is necessary to have simple and objective tools to detect fluctuations in the motor status of patients and closely monitor their response to treatment.

Here, current difficulties and barriers to Parkinson's disease management are described. In addition, the role of new technologies is introduced as potential supporting tools to provide a more holistic approach to the treatment of the disease. For all these reasons, the need of having multidisciplinary teams accessible to the patients is also discussed.

In summary, Parkinson's disease is a complex and multisystem disorder that requires a multidisciplinary and holistic approach compressing all the aspects of the disease to improve the quality of life of the patients. New technologies are a growing field that could provide a potential solution to the current unmeet of this disabling disease by real-time remote monitoring.