In this introduction, we lay the groundwork and make a case for an interdisciplinary scholarship as it pertains to spatial research that deals head-on with labyrinthine processes of spatiality and supersedes jigsaw-like, Euclidean spatial conceptualizations. To put it another way, not only is it necessary to “turn to” space, but also, and perhaps most importantly, space needs to be reconceived for contemporary phenomena to be substantively assessed. The fundamental elements of the contributions contained in this volume, which have been clustered around diverse thematic common denominators (spatiality and temporality; spatiality, inequality, and the economy; digitization and visualization of space; and imagining, producing, and negotiating space) and succinctly reviewed, evince that space does not simply enable a relatively uncritical and passive reflection on social phenomena, but rather constitutes both a representational and constitutive analytical strategy that allows bridges to be built across disciplines. This in turn enables fruitful exchanges between diverse and insightful research perspectives, thus making it possible, as is the case in this book, to navigate spatial transformations through the lens of the refiguration of spaces.