Higher education has never been a place of acceptance and inclusion. There has been a problem of Otherizing international students in and outside the classroom, and the Othering has become rapidly intensified following COVID-19’s global impact. Othering is the process of turning one as the Other in opposition to us based on perceived differences. It can result in social exclusion and other challenges for those distinguished as the Other. Focusing on Othering as the core concept, this chapter will present a picture of its causes, mechanisms and consequences in higher education. Othering is a two-way process. In addition to examining international students’ narratives of how they feel Otherized in receiving countries, this chapter will scrutinize their perspectives at the same time and depict how they Otherize locals at the same time. Finally, this chapter will provide several practical suggestions on how to conduct research on Othering in the future.