This chapter examines Greece’s position towards the European strategic autonomy initiative. As a NATO ally but also a small European Union state in a precarious geographical position, with a history of various occupations that violated its sovereignty, and an ongoing track of tensions with Turkey, Greece sees ESA as an opportunity to secure its interests in the region. The chapter explores the current trends in Greece’s defence and security policy, the views of its political and military elite on the ESA initiative, and the delicate balance Greece must strike between its commitments to the EU and NATO. Finally, it discusses how the 2022 war in Ukraine has brought concerns about the role Greece and the EU must play in European security and stability.