Many relevant adults who are invested in young people’s health and wellbeing (including teachers, parents/guardians, health professionals/practitioners, policy makers) are aware that young people are prolific users of social media, but they are uncertain about how to support young people in their engagement with health-related digital media. In this chapter, we review the evidence presented in the previous chapters and provide evidence-based guidance for educators, policy, and researchers. We consider clear challenges in the process of meeting the needs of multiple stakeholders and knowledge translation, and evaluate the effectiveness of the pedagogical case model as a professional development tool.