ABSTRACT

Environmental assessments are concerned with the effects of some sort of exposure. Exposure is the contact or co-occurrence of a chemical or other agent with a receptor. As explained in Chapter 5, the exposure can be anything from an airplane spraying a field to a chemical binding with a receptor on a cell surface. We assessors commonly think about exposure as the exposure metrics in exposure–response relationships derived from toxicity tests, observational studies, or models. However, as introduced in Chapter 5, the exposure that is ultimately important to the assessment is the one that will be regulated, remediated, or otherwise managed.