ABSTRACT
This chapter concerns the formation of the osteoinductive and osseointegrating properties of the bone-contacting surface of the multi-spiked connecting scaffold (MSC-Scaffold) prototype by electrochemical deposition (ECD) of calcium phosphates (CaPs). The chapter presents the results of preliminary attempts to modify the bone-contacting surface of the MSC-Scaffold preprototypes by ECD of CaPs carried out at constant current densities. It describes the process and the results of CaP potentiostatic ECD on the surface of spikes with the subsequent immersion of the MSC-Scaffold preprototypes in a simulated body fluid (SBF). The results of research in human osteoblasts culture of the calcium phosphate-coated prototype MSC-Scaffolds, as well as the results of the evaluation of their biointegration with bone as implanted under the articular surface of swine knee joints are presented.
