ABSTRACT
Objectives: This study investigate traditional uses of katuk leaves in Cireundeu and evaluate their antioxidant activity. Methods: this research combined observational ethnomedicine and experimental antioxidant assays. Ethnomedicine data were collected from 65 villagers and validated via triangulation. Antioxidant activity was analyzed using phytochemical screening, DPPH and FRAP assays. Statistical analysis used an independent t-test(p<0.05). Results: 90.28% of respondents use katuk leaves to enhance lactation and throat conditions. Phytochemical include flavonoids, alkaloids, saponins, and more. DPPH assay showed an IC50 of 3.78 ± 0.01 µg/mL; FRAP showed 47.85 mgQE/g extract. Conclusion: Katuk leaves demonstrate strong antioxidant activity, supporting their traditional use and potential application as an anti-inflammatory agent, in modern treatments, including orthodontics.
