ABSTRACT

The results of the very large Cancer and Steroid Hormone Group (CASH) case-control study of breast cancer were widely regarded as providing strong evidence against the conclusions of several other studies that had produced evidence of a significant increase in breast cancer among young women who had used oral contraceptives. For example, the CASH researchers had stated that their results ‘suggest that use of oral contraceptives by young women in the United States has no effect on the aggregate risk of breast cancer before 45 years of age’.