This chapter introduces the key factors and conditions that are used as analytical frameworks for the QCA application in this book. The chapter details several important factors that should be considered in an analysis and why, with a focus on explaining how certain factors can be crafted as heuristic devices in studying complex interactions. These include factors related to different resistance strategies, government actions and roles, geographic contingencies, and the actions of corporations and third parties, in addition to the contextual features of the studied polities. This chapter explains how the focus of attention and delimitation of the studied phenomena can potentially affect the study results. In addition, I will explore the benefits of focusing on a specific set of issues, such as resource politics and political ecology in a sectorial manner, rather than making overtly generalized claims based on a blurred database with multiple issues under consideration. This helps in the crucial task of explaining and showing how to calibrate data, that is, how to get from qualitative data to QCA.