ABSTRACT

The procedures in Sub-chapters 8.2 and Chapter 9 follow the flowchart depicted in Fig. III.1.

The essence of Part III is in Chapter 9 on ‘Plots, Fits, and Data Interpretation’. Chapter 9 is a step-by-step instruction on how to obtain estimates for system constants, such as the maximal obtainable effect (Rmax) or maximal binding (Bmax), and the apparent affinity of a drug (appKs), when based on one’s selection of the most likely hypothesis for an underlying reaction scheme. Thus, Chapter 9 is a hands-on of how to present data, fit parameters of theory to data, and interpret the results.