ABSTRACT

What happens when two drugs are given simultaneously? This book is about the analysis of data from ligand receptor interactions obtained from doseresponse experiments at equilibrium and about how theoretical schemes of mechanisms can be adopted to these data and with a main aim on how to simulate physically what happens when two drugs are given simultaneously. This for a comparison with reality and for a better implementation of combinational drug therapy. In essence, the entire book is an elaboration of the MichaelisMenten equation.