ABSTRACT
Drug delivery to the eye is not an easy assignment. The cornea, being a very important component in the visual pathway, is well protected by a number of very effective defense mechanisms, e.g., blinking, high tear secretion rate flushing its surface, induced lacrimation and tear protein production in response to foreign substances, etc. These protective mechanisms provide a challenge for pharmaceutical scientists to design drug delivery systems that can deliver therapeutic agents in sufficient concentrations to target sites.
