Classical flow cytometry is a very mature field and hence the demands on the light source, the detector and the optical system are very high. Flow cytometry has become a standard technique in cell biology and medicine. Commercially available flow cytometers have grown in complexity and performance, making use of multiple laser sources and an increasing number of detectors. This chapter summarizes the requirements of a microflow cytometer in terms of illumination source, optical detection and optical system. The state-of-the-art of the available organic photonic components is overviewed. The two parts are converged, and the real potential of organic photonics for microflow cytometry is investigated. Organic photonics devices are based on either small semiconducting molecules — mainly deposited by vacuum phase approach — or semiconducting polymers — deposited by liquid phase processes such as printing.