ABSTRACT

The adhesion and biofilm formation ability of several important pathogens continues to be a problem for medical devices and one of the most common reasons of implant failures. Due to this fact, significant necessity exists of medical devices that can intrinsically resist to microbial colonization. In recent years, several approaches have been investigated and generally present an effective means to reduce microbial adhesion and thus prevent biomaterial-associated infections. These strategies involve the modification of surfaces mainly by the application of biomaterials coatings. This chapter focuses on several of these strategies.