Insulin-dependent diabetes mellitus (IDDM), previously known as juvenile-onset diabetes and also referred to as Type I diabetes, is the most common metabolic disorder of childhood. Estimates indicate that approximately 120,000 youngsters in the United States are affected by this disease. For these individuals, survival depends on exogenous insulin administration and a very demanding and complex treatment regimen to balance insulin levels with food intake and energy expenditure, in an effort to approximate normal glucose metabolism.