ABSTRACT
The application of radionuclides in biomedical studies has not only provided a wealth of knowledge in basic medical science but also helped in the management of patients. The application of radionuclides in biomedical studies has not only provided a wealth of knowledge in basic medical science but also helped in the management of patients. The basic principle for the estimation of circulating blood volume depends on the measurement of the dilution of a known quantity of a nondiffusable radioactive compound in the vascular compartment. The technique for the radiolabeling of any cell depends on the biochemical interactions of a radioactive precursor during the development or metabolism of the cell. Radionuclide labeling of thrombocytes have not only been useful in kinetic studies but their survival and sequestration studies have been valuable in clinical investigation. The availability of artificially produced radionuclides led to their applications in biomedical investigatio.
