ABSTRACT
The main challenge of nanotechnology is to develop a strategy for molecular therapy which can circulate in the body without being detected by the immune cells and still be able to deliver specifically to the diseased region. Various metallic and their derivative nanoparticles (NPs) and their organometallic counterparts have been found to have promising anticancer activity on broad classes of cancer. Gold NPs have the ability to act as an enhancer for radiation dose and can also be used for therapeutic drug carriers. Dose-dependent anticancer activity has also been found in MCF-7 breast cancer cells with silver NPs, leading to induction of apoptosis with even nanogram concentration ranges. Copper NPs are among the NPs synthesized via modern-day technologies that have interesting biological and physiochemical properties. Targeted cancer therapy can distinguish the slight differences between cancer and normal cells. Dendrimers have been widely used for gene and drug delivery for cancer therapeutics.
