ABSTRACT

Schizophrenia and other mental disorders are increasingly coming to be understood as multidimensional conditions that include medical dysfunction in addition to clinical, neuropsychological, social, and neurobiological dimensions of disorder. The extent to which medical dysfunctions overlap with clinical problems in schizophrenia is part of an important debate about the conceptualization and treatment of psychotic disorders. Similarly, the extent to which medical disorders contribute to neuropsychological dysfunction has a significant bearing on the extent of cognitive and function deficits, and on the identification of useful measures for therapeutic interventions.