ABSTRACT
Aiming to provide an unified theory of ionic liquids’ ecotoxicity the recent spectral structure-activity relationship (SPECTRAL-SAR) algorithm is employed for testing the two additive models of ionic liquid activity: the parametric (abbreviated as |0+>) and the endpoint (abbreviated as |1+>) models accounting for the causal and observed interactions between the anionic and cationic subsystems, respectively. As a working system the Daphnia magna ecotoxicity was characterized through the formulated and applied spectral chemical-biological interaction principles. Specific anionic-cationic rules of interaction along the developed mechanistic hypersurface map of the main ecotoxicity paths together with the so called resonance limitation of the standard statistical correlation analysis were revealed.
