The development of self-regulation is known to be influenced by children’s experiences and relationships. What is the role of parental scaffolding, in particular? Scaffolding involves supporting children with just enough, but not too much, guidance. In this entry, biological, psychological and cultural factors that explain variations in how parents scaffold their children’s self-regulation are examined. Evidence that there are reciprocal influences between parents and children when it comes to developing self-regulation is also reviewed.